Meaning & Origin
A surname from Spanish.
Santana is a unisex baby name of Spanish origin, an elaboration of Santa — the feminine form of Saint — meaning "holy" or "sacred." It has deep roots in Latin American Catholic tradition and is also a well-known Spanish place name.
The name's global fame rests largely with Carlos Santana, the legendary Mexican-American guitarist whose band Santana has been one of the most influential rock acts since the late 1960s. That association gives the name an irresistibly musical, soulful energy.