Maizie is a variant spelling of Maisie, itself a Scottish diminutive of Margaret from the Greek Margarites, pearl. The -ie ending gives it extra warmth that the more common Maisie doesn't quite have. It's a name with the soft, slightly old-fashioned quality of names given a generation ago and now being rediscovered as charming.
The Scottish Diminutive Tradition
Maisie and Maizie come from the same Scottish naming tradition that produced Jessie, Bessie, and Nellie: diminutives that became standalone names with their own warmth. Cavalier King Charles Spaniels and Cocker Spaniels suit Maizie's combination of gentle warmth and slight formality.
Human-Pet Crossover
The human name Maisie (standard spelling) has been climbing, boosted by Game of Thrones actress Maisie Williams. The pet version benefits from that cultural traction. Maizie specifically is rarer, giving it slightly more personality than the standard spelling.
Counter-Reading: Spelling Fragmentation
Maizie at rank 2079 with 47 records almost certainly fragments with Maisie, Maisy, and Mazey. The combined count for all variants would rank substantially higher. This is a clear data artifact: the name itself is meaningfully more common than any single spelling's count suggests. Browse other vintage diminutive pet names.